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Enable AI-aided antibody development

With a wealth of machine learning and data science expertise, we’ve developed our own deep learning models and engaged in numerous pharma and biotech collaborations. Whether you’re looking for assistance in building new generative AI models, utilize our models to e.g. streamline your humanization work, or optimally equip your ML experts with a scalable platform to manage and analyze your data, we have the expertise and tools to keep you at the forefront of innovation.

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Develop your AI models with experts

Solid AI models are built upon well-curated datasets. Using our extensive knowledge of antibody sequences, we have meticulously curated public datasets to train our own PLMs (protein language models). While deep learning models excel at recognizing patterns of protein sequences, we are continuously working on the ways to benchmark our models and derive meaningful biological insights from them. If you would like to partner on model development or use our pre-trained models to strengthen your research, don’t hesitate to reach out! We can:

  • Train new language models from proprietary datasets or share our insights
  • Enable our in-house models for your prediction tasks while ensuring data privacy
Gergana Bounova sitting at a table with a laptop.

Accelerate antibody humanization with our lab-validated ML model

Our generative deep learning model overcomes the drawbacks of both traditional grafting approaches, which are often time and resource-intensive, and public deep learning models like BioPhi, which typically fail to retain binding sufficiently (or at all). Building on our proprietary AIGX protein language models (PLM), a generative interface was trained to create humanized variants of parental species. With outstanding success rates per generated candidate, it brings significant time and cost savings.

  • Highly efficient at preserving binding affinity of parental antibodies
  • Ensures higher success rates with fewer screened candidates
  • Enables humanization of many candidates early in your research
  • Flexible configuration
Humanization process shown through antibodies.

GenovacAI™ humanization service – powered by ENPICOM

Genovac, a leading CRO in antibody discovery, expression, and characterization, and ENPICOM partnered to provide a fully integrated humanization service. By combining ENPICOM’s generative AI model with Genovac’s state-of-the-art lab facilities and expertise, we offer a comprehensive and cost-effective service from parental sequence to expressed and fully screened humanized antibodies. Our humanization model has been successfully validated, showcasing its exceptional performance compared to open-source alternatives like BioPhi. Detailed supporting data is available upon request.

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Enabling AI aided biologics development with the IGX Platform

Are you looking to utilize your AI model in drug discovery or streamline data management for model training? Our scalable data analysis platform allows you to seamlessly manage your data and integrate with a variety of internal and external data sources through APIs, easily extract well-structured data for training advanced AI models, and easily annotate new datasets in bulk.

IGX-Track graphic view of bar plots.
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Talk to us about your project
A scientist using IGX-Branch on their computer in a lab.