Services
ENPICOM excels at the interpretation of immune repertoire sequencing (Rep-Seq) data, drawing on deep expertise in immunology, bioinformatics, statistics, and software engineering. Embedded in the scientific community, we continuously follow and implement the latest developments, ensuring you benefit from the most advanced analysis methods. All our services are tailored to your needs. Have a look below and contact us to meet with our research team.
Full-service repertoire sequencing
- Human and mouse, BCR and TCR
- 5’ RACE, unique molecular identifiers (UMI)
- Wet- and dry-lab workflow integration
- Extra quality control measures
From sample to discovery
Together with Cerba Research's state-of-the-art laboratory specialized in (molecular) diagnostic testing and assay development, we deliver full immune repertoire sequencing and analysis service. Starting from sample material (e.g., blood or tissue) or extracted template material, we provide you with a full-service proposition: sample preparation, sequencing, data analysis, visualization, and reporting. If you opt to use our discovery analysis platform, this will allow you to interrogate your data yourself – without coding - to get to the best possible insights.
Repertoire analysis
Our team is up to date on the latest developments in the immunogenomics field and can assist you with any aspect of repertoire analysis. From the processing of specific sequencing constructs to the statistical analysis of clonotype data. We can perform small research pilots up to large contract research projects.
- Candidate selection
- Analysis of patient cohorts
- In-depth quality control of new libraries
- Support for custom references and sequencing protocols
- Application of new published or experimental methods
- Comprehensive analysis reporting
Antibody humanization
Transform your antibody candidates into effective therapeutics with our cutting-edge humanization service. Unlike traditional grafting methods, which are time-consuming and can compromise binding affinity, our generative deep learning approach eliminates the need for grafting altogether. Leveraging our proprietary AIGX protein language models, we provide a service that achieves higher success rates with fewer screened variants. Our lab-validated model significantly outperforms other machine learning methods like BioPhi, ensuring optimal retention of binding affinity across diverse parental species.
Deliverables
Custom reports
Custom reports tailored to your needs. Consult with our technical experts to discuss your more advanced analysis needs and get to the desired insights even faster.
Access to any data files
All data files, including those generated during intermediate steps, are made available.
Publication-ready graphs
We provide publication-ready graphs and descriptions to help you with your next (scientific) publication.