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IGX Platform

An intuitive cloud solution that enables any scientist to efficiently manage, analyze, and visualize immune repertoire sequencing data.

Unlock the full potential of your repertoire data

The IGX Platform is an end-to-end cloud solution that removes the complexity of managing and analyzing immune repertoire sequencing data. Technology-agnostic and code-free, it enables every scientist to focus on the research and maximizing valuable insights.

  • Work with T and B cells, NGS and Sanger
  • Integrate data from any source
  • Intuitive user interface and visualizations
  • Always on, ready to scale

Clone Browser. Organized.

  • No matter the source, all your data is harmonized once it hits the platform. Regardless of whether you work with B or T cells, want to bring together data from Sanger and NGS experiments, or even if you have data generated using other platforms. Your data is harmonized upon import, allowing comparisons between datasets and ensuring compatibility with all IGX Apps.

  • The IGX Platform has a flexible tagging system designed to capture any kind of annotation or metadata. Tags can be anything you need: descriptive (e.g., a study identifier, or a disease diagnosis) or quantitative (e.g., affinity or avidity), providing virtually infinite ways to organize your data. Tags can be applied at any level – sample, cell or even sequence – and are used throughout the platform: for finding your data, but also to generate interactive visualizations.

  • Forget looking for and searching through countless Excel sheets. The IGX Platform stores all your data in one place, and provides a powerful search engine, optimized for repertoire data. Searches can be used in a variety of different workflows such as: improving data quality by identifying and excluding contaminating sequences or finding that one clone relevant for your research. Once you have dialed in your search just right, save it with a single click.

  • Collections are what we call samples. They store sequences coming from bulk or single-cell experiments and are automatically created when you import your data. We provide multiple ways to tag them with your clinical or experimental metadata, so your annotations are never lost and always where you want them: ready to be used in your next analysis.

Compose your perfect workflow

The IGX Platform comes with Apps that tackle specific challenges and use cases. Pick and choose Apps to build the end-to-end workflow that fully covers you needs, whether that means finding that needle-in-a-haystack antibody or identifying response patterns in patients in clinical trials.

Secure data sharing

  • Data Spaces on the IGX Platform provide secure locations to compartmentalize any data generated in your organization, team, or project. Data Spaces can be private to a single user, shared between project members or organization, or even made available to collaborators from other organizations.

  • Read-only Data Spaces are perfect for antibody service providers and contract research organizations, as they provide secure environments to share data with customers, without the risk of data modification. Customers can explore generated data visually through IGX Apps and easily download raw data.

What sets IGX Platform apart?
Make the most of your data

Work with a wide variety of raw and processed repertoire data types; it is automatically harmonized, so you can immediately start your analysis.

Annotate to enrich your analysis

Link clinical annotations and experimental results to samples, cells, or sequences and generate information-rich visualizations.

Work with single cells

The IGX Platform and its Apps automatically keep track of paired receptor chains. Working with single-cell data has never been easier.

Secure data sharing
Collaborate and share

Take control of data within your organization and share it with clients or collaborators using Data Spaces.

Choose your clonotype definitions

Choose clonotype definitions that are perfectly tailored to the biological question you aim to answer.

Skip the code

Work with an intuitive user interface and accomplish complex tasks without translating biology to code, so you can focus on what matters most: your research.

Stay in sync

The IGX Platform securely runs in the cloud, which means you’re always in sync and accessing the latest and greatest. Store billions of sequences and run large analyses with confidence and ease.

Leverage public databases

Compare your sequences to curated public databases to discover hints on antigen specificity or patentability.

Rely on professional development & support

The IGX Platform is built from scratch with professionally developed, thoroughly tested code and has on-demand support.

ENPICOM’s IGX Platform is unique in its kind. It is the only analysis and data management platform specifically designed for this type of sequencing data. IGX offers us flexibility, ease-of-use, data integration, and data sharing possibilities – all criteria that we consider extremely important to properly support our scientific work.

Dr. Trevor Pugh, Senior Scientist at the Princess Margaret Cancer Centre

Use cases

  • High-throughput bulk repertoire sequencing has proven to be a powerful technology to interrogate repertoires at a much larger scale and is therefore ideal to identify relatives of hits with increased affinity and developability attributes.

    With the IGX Platform, you can annotate clones from both Sanger and NGS technologies and link available assay data. IGX-Cluster and IGX-Branch compute interactive, information-rich phylogenetic trees for clusters of interest. This provides a versatile system to discover promising antibody candidates from the NGS pool present in the vicinity of well-characterized Sanger sequences – with improved properties – for follow-up analysis.

  • The Clone Browser, in combination with the downstream analyses of IGX Explore, provide a seamlessly integrated workflow for the exploration and identification of response patterns from in vitro experiments or patient cohorts. The V/J Gene Usage plot is an interactive visualization that allows you to easily stratify data into groups and discover preferential gene usage in treated samples or patients.