IGX platform

Apps

Different analyses and visualization methods are organized on the platform in separate units called Apps. Apps are independently developed and fully integrated with the Clone Browser, allowing for reproducible, end-to-end workflows.

IGX-Profile performs state-of-the-art clone identification and quantification.
Starting from raw sequencing files, IGX-Profile identifies clones with outstanding accuracy by using proprietary adaptive error correction technology (link to benchmarks). The profiled clones are immediately available for metadata tagging and downstream analysis with IGX-Explore.

IGX-Explore features four downstream analyses. Customizable, interactive visualizations enable the exploration of repertoire characteristics such as CDR3 length, diversity, clone overlap, and shared gene usage. Intuitive controls such as toggles, sliders and lasso selections allow the user to easily explore and customize plots. Check out this use cases to see how IGX Explore can be used to identify expanded clones in bulk T cell repertoires (link to use cases).

Check out these use cases to see how IGX Explore can be used to identify expanded clones in bulk T cell repertoires.

IGX-Inspect allows the user to analyze the quality of raw sequencing data (FASTQ) as well annotated clone summaries processed by IGX-Profile. Batch and sample level quality statistics are coupled through interactive visualizations, allowing users to easily identify batch effects, and perform thorough inspection on samples of concerning quality.

Continuous App development

New Apps are continuously being developed and will be made available through incremental software updates of the IGX platform.

Fitted to your requirements

Tailored software extensions to answer specific research or clinical questions can be custom-built or co-developed, in collaboration with ENPICOM’s team of experienced immunologists, bioinformaticians and software engineers.