IGX Platform

Apps

Different analyses and visualization methods are organized on the platform in separate units called Apps. Apps are independently developed and fully integrated with the Clone Browser, allowing for reproducible, end-to-end workflows.

IGX Platform modular architecture
IGX-Profile

IGX-Profile performs state-of-the-art clone identification and quantification on bulk sequencing data. Starting from raw sequencing files, IGX-Profile identifies clones with outstanding accuracy by using proprietary adaptive error correction technology. The profiled clones are immediately available in the Clone Browser for metadata tagging, quality control with IGX-Inspect and downstream analysis with IGX-Explore.

IGX-Explore

IGX-Explore generates intuitive visualizations which provide insight into the dynamics of the immune system. It includes several analyses with interactive plots: V/J Gene Usage, Diversity Measures, and CDR3 Length Distribution. Intuitive controls such as toggles, sliders and tooltips allow the user to easily explore and customize plots.

IGX-Inspect

IGX-Inspect allows the user to analyze the quality of raw sequencing data (FASTQ) as well annotated clone summaries processed by IGX-Profile. Batch and sample level quality statistics are coupled through interactive visualizations, allowing users to easily identify batch effects, and perform thorough inspection on samples of concerning quality.

IGX-Compare

IGX-Compare is an application to compute and visualize common clones (clonal overlap) between different sets of receptor sequences. IGX-Compare can be used to compare different patient cohorts in one or more studies, or to compare internal results with external databases such as ImmuneACCESS and the VDJdb, leveraging their additional annotations to generate new insights.

Scale your immunomics research

The component services of the IGX Platform can be scaled up (more computational power) and scaled out (larger number of computational nodes) independently, to ensure maximal responsiveness while handling large amounts of data. Apps can also be scaled as needed, independently of other Apps and the platform itself, in order to ensure top- notch performance when analyzing large datasets.

Learn more about the IGX Platform specifics

Continuous App development

New Apps are continuously being developed and will be made available through incremental software updates of the IGX platform.

Fitted to your requirements

Tailored software extensions to answer specific research or clinical questions can be custom-built or co-developed, in collaboration with ENPICOM’s team of experienced immunologists, bioinformaticians and software engineers.

Software engineering