ENPICOM at BioSB 2018, 4th Dutch Bioinformatics & System Biology Conference

ENPICOM presented at BioSB 2018, 4th Dutch Bioinformatics & System Biology Conference On May 16, […]

ENPICOM presented at BioSB 2018, 4th Dutch Bioinformatics & System Biology Conference

On May 16, 2018, at the BioSB 2018 conference, ENPICOM’s Chief Scientific Officer Nicola Bonzanni presented the scientific poster “Scalable end-to-end immune repertoire analysis: the ImmunoGenomiX Platform”

Please click here for the abstract book of the conference, which includes ENPICOM’s poster:

High-throughput sequencing of the immune repertoire is increasingly used for monitoring tumor biomarkers and evaluating the performance of immunotherapeutics for cancers. However, most of the available tools are not designed to track and investigate the dynamic nature of B and T cell receptor repertoires across multiple time points or between different patient cohorts in a clinical context.

We introduce the ImmunoGenomiX Platform – an end-to-end immune repertoire analysis platform that is currently under development. This platform allows quantitative characterization of immune repertoires from sequenced B or T cell receptors. The modular structure of the ImmunoGenomiX Platform and its integration with data management systems allows users to manage and process large clinical studies, stratify patients, filter clonotypes and interactively explore analysis results.

Using TCR sequencing data, we show how the intuitive graphical user interface of the ImmunoGenomiX Platform makes analysis and interpretation of repertoire data accessible to clinicians and biologists alike, without the need for computational expertise.