IGX Platform 2.0 supports the storage, annotation and analysis of paired receptor chains and includes new search options specifically tailored to the structure of paired receptor data, making it easier than ever to find and analyze your single-cell data.
Powerful comparison analyses
With IGX-Compare, users can compare any two data sets and easily visualize and prioritize matching clones. For instance, by matching a single clone against an external database or by finding the overlap between two internal patient cohorts.
Flexible at the frontend
IGX currently supports Illumina FASTQ data from BCR (heavy, lambda, and kappa chains) and TCR (alpha and beta chains) sequencing experiments from both DNA and RNA of human and murine samples, as well as annotated clones from various data sources.
First-in-class clone identification
Correct identification and quantification of receptors is a crucial and fundamental step in the analysis of immune repertoires. Extensive head-to-head benchmarking studies versus popular tools in the field show that IGX-Profile shows superior performance in the correct identification of both B and T cell clones.
Scales according to your needs
The IGX Platform automatically scales its resources, which ensures maximal responsiveness and execution performance, irrespective of the amount of data you want to work with.
Secure cloud deployment
The IGX Platform is delivered through a Software as a Service (SaaS) model, hosted centrally and available instantly to every user via their web browser. The SaaS approach eliminates deployment time, substantially reduces maintenance costs and ensures that users always have access to the latest version of the IGX Platform. All communication to and from the platform is encrypted and validated by a certified independent authority in order to ensure secure and private access.
The cloud-based IGX Platform allows users to have instant access to the latest version of the platform and its Apps.
Reproducibility through version control
All previous versions of Apps remain available for analyses in order to ensure perfect reproducibility of results and consistency during the entire drug development process.
Market authorization support
The IGX Platform has been developed following the principles of the IEC 62304 standard, a framework that facilitates safe design and maintenance of medical device software. The structured lifecycle process ensures reliability of the end-result and reduces the regulatory compliance burden of products developed using the IGX Platform, thereby accelerating the drug development process.